What Contributes to Longevity?

The biggest factors that contribute to longevity are diet, lifestyle, and genetic, social, and environmental factors.

Obesity, poor blood sugar control, smoking, and alcohol abuse contribute greatly to earlier death. In many cases, these factors are the underlying contributors to the two major causes of death, namely heart disease and cancer.

Top Anti-Aging And Longevity Supplements

My general recommendation as far as supplements go is to make sure that your nutritional foundation is strong. In addition to a health-promoting diet, I believe the following key supplements are important as foundational approaches to anti-aging and longevity:

1. Multivitamin: A high-potency multiple vitamin and mineral formula to provide a nutritional “insurance policy” that ensures all essential micronutrients are provided in sufficient amounts. 
2. Vitamin D: Extra vitamin D3 because deficiency is very common (at least 50% of the general population). Higher vitamin D3 levels are associated with a 5-year difference in telomere length. What this means is that a 70-year-old woman with higher vitamin D3 levels would have a biological age of 65 years. Take a daily dosage of 2,000 to 5,000 IU of D3.
3. Omega-3: A pharmaceutical-grade, high-quality fish oil supplement sufficient to provide a combined total of 1,000 to 2,000 mg of EPA+DHA daily. Results from the DO-HEALTH trial, a large European clinical trial that investigated the effects of vitamin D3, omega-3 fatty acids, and a home exercise program on healthy aging in older adults found that omega-3 fatty acids (1,000 mg daily) and vitamin D3 (2000 IU daily) significantly slowed biological aging by approximately 2.9 to 3.8 months over the three-year study. And while omega-3s alone reduced biological aging in the three measures of biological aging, the combination of omega-3s, vitamin D3, and exercise produced the greatest effect, suggesting a possible synergistic benefit.
4. Turmeric: A plant-based antioxidant. For anti-aging and longevity benefits, consider taking curcumin, the active compound found in turmeric (Curcuma longa). Curcumin exerts a multitude of effects that fight aging and promote longevity, but it is its profound effects on inflammation that make it so important. These beneficial effects have been observed in clinical studies showing certain curcumin preparations (most notably Theracurmin®, Meriva®, and C3 Complex®) to produce positive effects in protecting against brain aging, promoting joint health, and improving metabolism. 

To build upon this foundation, I would recommend focusing on supplements that work to support glutathione, enhance mitochondrial function, exert a positive effect on autophagy, and reduce silent inflammation.